Donnie's just at bad at gauging when people lie as he is at lying himself, but he knows his brothers. And even if it isn't an outright lie, what Mikey supplies him with is still...weird. On an entirely different level of weird as opposed to normal weird when Mikey is concerned.

"You don't usually get frustrated with cookies," he points out.

His brother knows cookies. Being on a ship shouldn't make a difference, not with the artificial gravity and all that, although Donnie isn't quite sure how that affects things being that he doesn't cook or bake himself. With that in mind he supposes that it's possible one can get frustrated with baking if the pressure isn't quite right, somehow, his expression shifting towards something more uncertain as his notorious overthink kicks in.